May 20, 2012

FDA Advisory Panels: No Means No, Yes Means Maybe

MD Becker Partners' Life Science Digest: FDA Advisory Panels - No Means No, Yes Means Maybe

As the only company to receive a positive United States Food and Drug Administration [FDA] Advisory Committee [AdCom] recommendation for a product candidate to treat obesity in 2010, Orexigen Therapeutics, Inc. (OREX) appeared well positioned to receive marketing approval for Contrave® [naltrexone HCl/bupropion HCI].  However, on January 31, 2011, Orexigen and its partner Takeda Pharmaceutical [...]

Biotech Deal Activity a Mixed Bag During Major Conference

MD Becker Partners' Life Science Digest: Biotech Deal Activity a Mixed Bag During Major Conference

Last week, thousands of registrants gathered in San Francisco, California for the JP Morgan Healthcare Conference [JPMHC] to hear 25-minute presentations from 364 life science companies.  For industry executives and investors, deal activity emanating from the annual event typically serves as a good barometer for the rest of the year. Adding to an already hectic [...]

Drug Development Spotlight: The mTOR’s New Clothes?

MD Becker Partners' Life Science Digest: Drug Development Spotlight - The mTOR’s New Clothes?

In 1837, Hans Christian Andersen authored a short tale titled The Emperor’s New Clothes.  The main character, so enamored by his appearance and his clothing that he had a different suit for every hour of the day, was swindled by a pair of weavers purporting that they could create clothing from a magical fabric that [...]

Cancer Vaccine Therapies: Failures and Future Opportunities

FIGURE 1: FDA APPROVAL OF CANCER MABS FROM 1997-2010

(Note: the following text is an Executive Summary from our new 150-page report titled “Cancer Vaccine Therapies: Failures and Future Opportunities”) Since the early 1990s, cancer immunotherapy has provided hope to patients, physicians, and investors as a new treatment modality with limited side effects and superior efficacy.  Cancer immunotherapy broadly includes passive immunization, active immunization, [...]

Ache-free Investment Opportunities in Neuropathic Pain

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In the United States, up to 50 million people live with chronic pain, with the majority of these patients not satisfied with their current pain treatments.  Pain is defined clinically as an unpleasant emotional experience resulting from real or potential tissue damage and is generally divided into two categories based on cause: Nociceptive pain, which [...]