monoclonal antibodies

February 7, 2012

FDA Approved Monoclonal Antibodies (mAbs) for Cancer Therapy

March 5, 2011 By MD Becker Partners 3 Comments

Graph of FDA Approved Monoclonal Antibodies (mAbs) for Cancer Therapy

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Filed Under: Facts & Figures Tagged With: alemtuzumab, bevacizumab, biotechnology, cancer therapy, cetuximab, FDA, gemtuzumab ozogamicin, ibrituxomab tiuxetan, ipilimumab, monoclonal antibodies, ofatumumab, panitumumab, rituximab, tositumomab, trastuzumab

Investment Opportunities with Five Frontline Therapies for AML

September 6, 2010 By MD Becker Partners 2 Comments

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Acute myelogenous leukemia [AML] is a fast-growing cancer of the blood and bone marrow. Unformed cells called myeloblasts, or “blasts,” reside in the bone marrow and normally become a particular kind of cell – a white blood cell, red blood cell, or platelet. In AML, abnormal blasts produce white blood cells that do not function [...]

Filed Under: Articles Tagged With: AC220, Acute myelogenous leukemia, Ambit Biosciences, AML, AraC, Astellas Pharma, azacitidine, blasts, CD33 receptor, CELG, Celgene, CEPH, Cephalon, clofarabine, Clolar, CYCC, Cyclacel Pharmaceuticals, cytarabine, Dacogen, daunorubicin, decitabine, Eisai, ESALF, farnesyltransferase inhibitors, FDA, Food and Drug Administration, gemtuzumab ozogamicin, GENZ, Genzyme Corporation, hypomethylating agents, idarubicin, JNJ, Johnson & Johnson, laromustine, lestaurtinib, lintuzumab, monoclonal antibodies, Mylotarg, nucleoside analogs, Onrigin, PFE, Pfizer, Sanofi-Aventis, sapacitabine, Seattle Genetics, SGEN, SNSS, SNY, SPA, special protocol assessment, sunesis, SuperGen, SUPG, tipifarnib, topoisomerase II inhibitors, Vidaza, Vion Pharmaceuticals, voreloxin, vosaroxin, Zarnestra

Monoclonal Antibody Companies Command Premiums

July 11, 2010 By MD Becker Partners Leave a Comment

Monoclonal antibody image from MD Becker Partners

Monoclonal antibodies, which have been approved for immunological, anti-infective, ophthalmic, cancer and other categories, represent one of the most successful therapeutic drug classes. Ten monoclonal antibodies have been approved for cancer therapy alone, including three blockbuster products sold by the Roche Group (RHHBY) – Avastin® [bevacizumab], Rituxan® [rituximab], and Herceptin® [trastuzumab] that collectively represented nearly [...]

Filed Under: Articles Tagged With: Abbott, Abgenix, ABT, adalimumab, Agensys, Alexion Pharmaceuticals, ALXN, Astellas Pharma, AstraZeneca, Avastin, Bayer Schering Pharma AG, BAYRY.PK, bevacizumab, biosimilars, BMY, Bristol-Myers Squibb, Cambridge Antibody Tech, CEPH, Cephalon, Ception Therapeutics, cetuximab, Domantis, Eli Lilly & Co, Erbitux, erlotinib, Facet Biotech, FDA, GEN.CO, Genmab A/S, GENZ, Genzyme, Herceptin, HGSI, Human Genome Sciences, Humira, ImClone Systems, IMGN, IMMU, ImmunoGen, Immunomedics, Inc., infliximab, KaloBios Pharmaceuticals, LLY, mAbs, MacroGenics, MedImmune, Micromet, MITI, monoclonal antibodies, MORG.DE, Morphosys AG, Morphotek, NASDAQ Biotechnology Index, NBI, NeuTec Pharma plc, OncoMed Pharmaceuticals, OSI Pharmaceuticals, PFE, Pfizer, Regeneron, REGN, Remicade, RHHBY, Rinat Neuroscience Corp, Rituxan, rituximab, roche, sanofi-aventis Group, Seattle Genetics, SGEN, SNY, Tarceva, trastuzumab, Tufts Center for the Study of Drug Development, XOMA

Cancer Vaccine Therapies: Failures and Future Opportunities

April 7, 2010 By MD Becker Partners 3 Comments

FIGURE 1: FDA APPROVAL OF CANCER MABS FROM 1997-2010

(Note: the following text is an Executive Summary from our new 150-page report titled “Cancer Vaccine Therapies: Failures and Future Opportunities”) Since the early 1990s, cancer immunotherapy has provided hope to patients, physicians, and investors as a new treatment modality with limited side effects and superior efficacy. Cancer immunotherapy broadly includes passive immunization, active immunization, [...]

Filed Under: Articles Tagged With: active immunotherapy, AGEN, allogeneic, Allovectin-7, American Society for Clinical Oncology, Antigenics, Arzerra, ASCO, autologous, Bavarian Nordic, BIIB, Biogen Idec, Biologics License Application, biotechnology, BiovaxID, Biovest International, BMY, Bristol-Myers Squibb Company, BVTI, cancer vaccine, CD20, CDX-110, Celldex Therapeutics, CTLA-4, Dendreon, dendritic cells, DNDN, EGFRvIII, Genmab A/S, GlaxoSmithKline, GM-CSF, gp100, GSK, GVAX, immunotherapy, ipilimumab, life sciences, lung cancer, MAGE-3, MAGE-A3 ASCI, MD Becker Partners, melanoma, monoclonal antibodies, NCI, NHL, non-Hodgkin’s Lymphoma, NSCLC, ofatumumab, Oncophage, passive immunotherapy, PDUFA, PFE, Pfizer, prostate cancer, prostatic acid phosphatase, PROSTVAC, Provenge, RHHBY, Rituxan, rituximab, Roche Group, sipuleucel-T, TRICOM, vaccine, Vical, VICL

Biotech Baker’s Dozen to Watch at Hematology Meeting

November 29, 2009 By MD Becker Partners 2 Comments

The 51st American Society of Hematology [ASH] Annual Meeting will take place December 5-8, 2009, at the Ernest N. Morial Convention Center in New Orleans, LA. This is the premier event for the hematology industry, attracting more than 20,000 hematologists and other health-care professionals. In this regard, Celgene Corporation (CELG) recently announced that data from [...]

Filed Under: Articles Tagged With: AEterna Zentaris, AEZS, Allos Therapeutics, ALTH, American Society of Hematology, ARIA, ARIAD Pharmaceuticals, Calistoga Pharmaceuticals, CELG, Celgene, chemotherapeutics, CYCC, Cyclacel Pharmaceuticals, Facet Biotech, FACT, GENT, Gentium SPA, HDAC inhibitors, IMGN, ImmunoGen, KaloBios Pharmaceuticals, kerx, Keryx Biopharmaceuticals, kinase inhibitors, monoclonal antibodies, nucleoside analogues, ONXX, Onyx Pharmaceuticals, PCYC, Pharmacyclics, pi3k, proteasome inhibitors, sapacitabine, Seattle Genetics, Semafore Pharmaceuticals, SGEN, small modular immunopharmaceuticals, SNSS, Sunesis Pharmaceuticals, TRBN, Trubion Pharmaceuticals